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Wagner's disease
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Wagner's disease : ウィキペディア英語版
Wagner's disease
Wagner's disease is a familial disease of the connective tissue in the eye that can cause reduced visual acuity. Wagner's disease was originally described in 1938. This disorder was frequently confused with Stickler syndrome, but lacks the systemic features and high incidence of retinal detachments. Inheritance is autosomal dominant.
==History==
In 1938 Hans Wagner described 13 members of a Canton of Zurich family with a peculiar lesion of the vitreous and retina. Ten additional affected members were observed by Boehringer et al.. in 1960 and 5 more by Ricci in 1961. In the Netherlands Jansen in 1962 described 2 families with a total of 39 affected persons. Both families had only ocular features. Alexander and Shea in 1965 reported a family. In the last report, characteristic facies (epicanthus, broad sunken nasal bridge, receding chin) was noted. Genu valgum was present in all. In addition to typical changes in the vitreous, retinal detachment occurs in some and cataract is another complication.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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